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O’Donnell PE, Ye XZ, DeChellis MA, Davis VM, Duan SZ, Mortensen RM and Milstone DS. Lipodystrophy, Diabetes and Normal Serum Insulin in PPARγ-Deficient Neonatal Mice. PLOS ONE. 2016:11(8):1-14. http://dx.doi.org/10.1371/journal.pone.0160636

Milstone DS*, Ilyama M, Chen M, O’Donnell P, Davis VM, Plutzky J, Brown JD, Haldar SM, Siu A, Lau AC, Zhu S-N, Basheer MF, Collins T, Jongstra-Bilen J, Cybulsky MI*. Differential Role of a NF-kappaB Transcriptional Response Element in Endothelial versus Intimal Cell VCAM-1 Expression. Circ. Res. 2015:117(2):166-177. *corresponding author.

Veronique T, Ciric A, Moretto-Zita M, Wolfe L, Li Y, Peng J, Maltepe E, Milstone DS, Parast MM. Hypoxia and Trophoblast Differentiation: A Key Role for PPARγ. Stem Cells Develop. 2013;22(21):2815-2824

Milstone DS. PPARγ in Angiogenesis and Vascular Development. Curr Angiogen 2012;1(3):192-205.

Rose JA, Rabenold JJ, Parast MM, Milstone DS, Abrahams VM, Riley JK. Peptidoglycan Induces Necrosis and Regulates Cytokine Production in Murine Trophoblast Stem Cells. American Journal of Reproductive Immunology. 2011 Mar 9.

Duan SZ, Usher MG, Foley EL 4th, Milstone DS, Brosius FC 3rd, Mortensen RM. Sex dimorphic actions of rosiglitazone in generalized peroxisome proliferator-activated receptor-gamma (PPAR-gamma)-deficient mice. Diabetologia. 2010 Jul;53(7):1493-505. Epub 2010 Apr 17.

Parast MM, Yu H, Ciric A, Salata MW, Davis V, Milstone DS. PPARg regulates trophoblast proliferation and promotes labyrinthine trilineage differentiation. PLoS ONE. 2009 Nov 30;4(11):e8055.

Ye CP, Duan SZ, Milstone DS, Mortensen RM. Go controls the hyperpolarization-activated current in embryonic stem cell-derived cardiocytes. Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H979-85. Epub 2007 Dec 21.

Duan SZ, Christe M, Milstone DS, Mortensen RM. Go but not Gai2 or Gai3 is required for muscarinic regulation of heart rate and heart rate variability in mice. Biochem Biophys Res Comm. 2007:May 25;357(1):139-43.

Duan SZ, Ivashchenko CY, Whitesall SE, D'Alecy LG, Duquaine DC, Brosius, FC III, GonzalezFJ, Vinson C, Pierre MA, Milstone DS*, Mortensen RM*. Hypotension, lipodystrophy, and insulin resistance in generalized PPAR-g deficient mice rescued from embryonic lethality. Journal of Clinical Investigation. 2007;117:812-22. *corresponding author.

Duan SZ, Ivashchenko CY, Russell MW, Milstone, DS*, Mortensen, RM. Cardiomyocyte-Specific Knockout and Agonist of Peroxisome Proliferator–Activated Receptor Both Induce Cardiac Hypertrophy in Mice. Circ. Res. 2005;97(4):372-9. *corresponding author.

Friedrich EB, Liu E, Sinha S, Cook S, Milstone DS, MacRae CA, Mariotti M, Kuhlencordt PJ, Force T, Rosenzweig A, St-Arnaud R, Dedhar S, Gerszten RE. Integrin-linked kinase regulates endothelial cell survival and vascular development. Mol Cell Biol. 2004;24(18):8134-44.

Yu Y, Moulton KS, Khan MK, Vineberg S, Boye E, Davis VM, O’Donnell PE, Bischoff J, Milstone DS. E-Selectin Is Required for the Anti-angiogenic Activity of Endostatin. Proceedings of the National Academy of Sciences. 2004;101(21):8005-8010.

Vernochet C, Milstone DS, Iehlé C, Belmonte N, Phillips B, Wdziekonski B, Villageois P, Amri, EZ, O’Donnell PE, Mortensen RM, Ailhaud G, Dani C. PPARg dependent and PPARg-independent effects on the Development of Adipose Cells from Embryonic Stem Cells. FEBS Letters. 2002; 510:94-8.

Jantzen H-M, Milstone DS, Gousset L, Conley PB, Mortensen RM. Impaired Activation of Murine Platelets Lacking Gai2. J Clin Invest. 2001;108:477-83.

Cybulsky MI, Li H, Chen M, Iiyama I, Iiyama K, Davis V, Gutierrez-Ramos J-C, Milstone DS. A major role for VCAM-1, but not ICAM-1, in early atherosclerosis. J Clin Invest. 2001;107:1255–62. Note: Comment by Ley and Huo, J Clin Invest. 2001;107:1209-1210.

Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW. The role of PPARg in macrophage differentiation and cholesterol uptake. Nature Med. 2001;7:41-7.

Jain M, Lim CC, Nagata K, Davis VM, Milstone DS, Liao R, Mortensen RM. Targeted Inactivation of Gai Does Not Alter Cardiac Function or b-Adrenergic Sensitivity. Am J Physiol Heart Circ Physiol. 2001;280:H569-75.

Nagata K, Ye C, Jain M, Milstone DS, Liao R, Mortensen RM. Gai2 but not Gai3 is Required for Muscarinic Inhibition of Contractility and Calcium Currents in Adult Cardiomyocytes. Circ Res. 2000;87:903-9.

Milstone DS, Redline RW, O’Donnell PE, Davis VM, Stavrakis G. E-selectin Expression and Function in a Unique Placental Trophoblast Population at the Fetal-Maternal Interface: Regulation by a Trophoblast-Restricted Transcriptional Mechanism Conserved between Humans and Mice. Dev Dynamics. 2000;219:63-76.

Milstone DS, O'Donnell PE, Stavrakis G, Mortensen RM, Davis VM. E-selectin Expression and Stimulation by Inflammatory Mediators are Developmentally Regulated During Embryogenesis. Lab Invest. 2000;80:943-954.

Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, Milstone DS, Spiegelman BM, Mortensen RM. PPARg is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro. Mol Cell. 1999;4:611-617.

Ye C, Sowell MO, Vassilev PM, Milstone DS, Mortensen RM. Gai2, Gai3 and Gao are All Required for Normal Muscarinic Inhibition of the Cardiac Calcium Channels in Nodal/Atrial-like Cultured Cardiocytes. J Mol Cell Cardiol. 1999;31:1771-1781.

Milstone DS, Bradwin G, Mortensen RM. Simultaneous Cre Catalyzed Recombination of Two Alleles to Restore Neomycin Sensitivity and Facilitate Homozygous Mutations. Nucleic Acids Res. 1999;27:e10.

Milstone DS, Fukumura D, Padgett RC, O'Donnell PE, Davis VM, Benavidez OJ, Monsky WL, Melder RJ, Jain RK, Gimbrone, MA Jr. Mice Lacking E-Selectin Show Normal Numbers of Rolling Leukocytes but Reduced Leukocyte Stable Adhesion on Cytokine-Activated Dermal Microvascular Endothelium. Microcirculation, 1998;5:153-171.

Gerritsen ME, Shen CP, Atkinson WJ, Padgett RC, Gimbrone MA Jr, Milstone DS. Microvascular endothelial cells from E-selectin-deficient mice form tubes in vitro. Lab Invest. 1996;75:175-184.

Gerritsen ME, Shen CP, McHugh MC, Atkinson WJ, Kiely JM, Milstone DS, Luscinskas FW, Gimbrone MA Jr. Activation-Dependent Isolation and Culture of Murine Pulmonary Microvascular Endothelium.  Microcirculation 1995;2(2)151-163.

Rimm IJ, Fruman DA, Abhyankar S, Sakamoto H, Orme IM, Milstone D, Seidman JG, Ferrara JLM.  T cell receptor (ß chain) transgenic mice have selective deficits in gd T cell subpopulations.  Transplant Immunol, 1994;2:218-224

Huttner KM, Pudney J, Milstone DS, Ladd D, Seidman JG. Flagellar and Acrosomal Abnormalities Associated with Testicular HSV-tk Expression in the Mouse. Biol Repro 1993;49:251-261.

Milstone DS, Shaw SK, Parker K, Szyf M, Seidman JG. An element regulating adrenal-specific steroid 21-hydroxylase expression is located within the Slp gene. J Biol Chem 1992;267:21924-21927.

Szyf M, Milstone DS, Schimmer BP, Parker KL, Seidman JG. Cis modification of the steroid 21-hydroxylase gene prevents its expression in the Y1 mouse adrenocortical tumor cell line. Mol Endo 1990;4:1144-1152.

Milstone DS, Parker CW. The glycoprotein nature and biosynthetic relationship of two molecularly distinct species of primate T cell growth factor. Biochem J 1986;236:371-377.

Howe RC, Milstone DS, Ratliff TL, Russell JH. Interleukin 2-mediated induction of lytic activity in a cloned murine CTL line. J Immunol 1985;134:2414-2418.

Milstone DS, Parker CW. Purification of primate T cell growth factor to apparent homogeneity by reverse phase high pressure liquid chromatography: Evidence for two highly active, molecularly distinct species. Biochem Biophys Res Comm 1983;115:762-768.

Milstone DS, Vold BS, Glitz DG, Shutt N. Antibodies to N6(∆2-isopentenyl)adenosine and its nucleotide: Interaction with purified t-RNA’s and with bases, nucleosides and nucleotides of the isopentenyladenosine family. Nucleic Acids Res 1978;5:3439-3455.